Annex 1 compliant cleaning and disinfection

Are you aware of the updated cleaning and disinfection guidance in GMP Annex 1? Here you can learn more about the new Annex 1 requirements and how to compliant by the deadline, through Ecolab’s bestselling range of contamination control products.

What is the update guidance on cleaning and disinfecting in Annex 1?

EU GMP Annex 1 states that for disinfection to be effective, prior cleaning to remove surface contamination should be performed. Cleaning programmes should also be designed to effectively remove disinfectant residues.

More than one type of disinfecting agent with different modes of action should be used for maximum effectiveness against bacteria and fungi. The periodic use of a sporicidal agent is also endorsed. A back up disinfectant may be required in case of a build-up in resistance to other agents.

Detergent

Klercide Neutral Detergent Sterile Spray is in demand following the release of the updated Annex 1! This sterile neutral detergent consistently, efficiently, and reliably removes soils and residues. It is formulated specifically for high-grade cleanroom environments and is available in a variety of ready-to-use formats.

Alcohol

Klercide 70/30 IPA Sterile Spray is a reliable IPA spray, designed for disinfection of cleanroom environments. It’s very suitable for a number of applications in GMP Grades A/B/C/D and is also available in a variety of formats.

Broad spectrum biocide

Klercide Low Residue Quat WFI Sterile Spray is a sterile ready-to-use daily disinfectant with low residue accumulation effect. It has broad spectrum bactericidal activity and can be used up to 10x without residue removal! It’s also available in a variety of formats.

Sporicide

Ecolab have a range of sporicides and the right one for your depends on your needs.

Residue management - Klercide Sporicidal Low Residue Peroxide Spray can be used up to 10x without residue removal. It’s suitable for daily disinfection for large and small surfaces, including but not limited to product contact areas and transfer disinfection.

User sensitivity – Klercide Sporicidal Enhanced Peroxide Spray can be used for daily disinfection for large and small surfaces, including transfer disinfection. It has less concentration, making it safer for some users that have sensitivity.

Excursion sporicide - Klercide Sporicidal Active Chlorine Sterile Spray can provide disinfection for transfer disinfection and following excursions and shutdowns.

Ecolab offers a wide range of programs, products, equipment and services to support and maintain clean environments, increase operational efficiencies, achieve sustainability goals, enhance safety and protect brand reputation.

Each unique formulation from Ecolab is available in a wide variety of ready-to-use formats. Browse the full Ecolab range on Cleanroomshop.